Apolipoprotein E, B Vitamins, and Cognitive Function in Older Adults

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Apolipoprotein E, B vitamins, and cognitive function in older adults.

Recognition of dated and contemporary famous faces, short-term memory, and visuospatial abilities were investigated in adults aged 75 years and older as a function of apolipoprotein E (APOE) genotype, epsilon4 or not epsilon4, and whether participants recorded normal or low levels of B vitamins. No associations between B vitamins and APOE were identified in respect to short-term memory or visuo...

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B Vitamins and Cognitive Performance in Older Adults: Review

A copious amount of scientific scrutiny has been dedicated to documenting typical and atypical human ageing, with a substantial body of work focusing upon the impact of lifestyle choices. One such lifestyle choice is that of diet and, in particular, micronutrient ingestion. Epidemiological studies have reported positive associations between B vitamin status and cognitive function, including neg...

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Apolipoprotein E and kidney function in older adults

BACKGROUND Previous studies suggest that the ε4 and ε2 alleles of apolipoprotein E (APOE) may be associated with decreased and increased risks of CKD, respectively, but there are limited data in older adults. We evaluated the associations of apolipoprotein E alleles with kidney function among older adults in the cardiovascular health study (CHS). METHODS Caucasian participants had APOE alleli...

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Neighborhood psychosocial environment, apolipoprotein E genotype, and cognitive function in older adults.

CONTEXT The social environment may influence cognitive function in aging. However, to our knowledge, no studies have investigated whether specific genes modify this association. OBJECTIVE To examine whether the apolipoprotein E (APOE) ε4 allele modifies the association of neighborhood psychosocial hazards and cognitive function. DESIGN A cross-sectional analysis. SETTING The Baltimore Mem...

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Apolipoprotein E, health, and mortality in Taiwanese older adults

Apolipoprotein E (ApoE), a commonly investigated genetic marker, has been linked to health outcomes and longevity. ApoE has three common alleles: E2, E3, and E4, with E3 being the most prevalent allele in most populations. The E4 allele is a common genetic risk factor for Alzheimer’s and cardiovascular disease (Corder et al., 1996; Eichner et al., 2002; Lahoz et al., 2001; Rosvall et al., 2009)...

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ژورنال

عنوان ژورنال: The Journals of Gerontology Series B: Psychological Sciences and Social Sciences

سال: 2005

ISSN: 1079-5014,1758-5368

DOI: 10.1093/geronb/60.1.p41